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ForumsRetatrutide & Triple AgonistsRetatrutide and fatty liver — MASH resolution rates in Phase 2 Page 3

Retatrutide and fatty liver — MASH resolution rates in Phase 2

MASHdoc_SA Mon, May 11, 2026 at 6:13 PM 23 replies 534 viewsPage 3 of 5
mona_PHX
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May 12, 2026 at 10:03 PM#11
PharmD_Rodriguez said:
The glucagon component looks paradoxical and is not.

This is exactly what I could not find anywhere else. I will report back once I have actually tried it.

Last edited: May 13, 2026 at 1:03 AM
40 13RetaRick_CA, JenPlateau, SallyK_inj and 37 others
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VendorMark
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May 13, 2026 at 8:09 PM#12

Adding the clinical framing, because it changes how the question reads. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

41 14KristenIndy, MarkLI_maint, Dr.PeteFamMed and 38 others
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Dr.GutHealth
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May 14, 2026 at 6:13 PM#13
Dr.EM_Chicago said:
The liver data is among the strongest non-weight findings in the class.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

42 15jennifer_SEA, tyler_CSCS, VanRx_Mike and 39 others
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SleepDoc_PDX
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May 15, 2026 at 4:18 PM#14

Adding the numbers, since they settle part of this. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

43 16sophie_paris, mel_PDX, Dr.AddMedPHL and 40 others
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Admin
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May 16, 2026 at 2:21 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.

44 17PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 41 others
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