TRIUMPH program trial design overview — all Phase 3 arms

One thing that is still open after JenPlateau’s answer:

How long did you give it before you decided it was working?

jason_paloalto said:

One practical note: write down what you did and when, before you need it.

Pushing back on jason_paloalto here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Carry on.

jason_paloalto said:

One practical note: write down what you did and when, before you need it.

Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.

Adding the clinical framing, because it changes how the question reads. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.