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ForumsTirzepatide (Mounjaro / Zepbound)5mg doing nothing - should I ask to go up? — need advice Page 3

5mg doing nothing - should I ask to go up? — need advice

Dr.LeslieOBGYN Tue, Sep 2, 2025 at 12:56 PM 12 replies 1,308 viewsPage 3 of 3
Dr.NephBHM_UK
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Sep 4, 2025 at 11:12 AM#11
ingrid_STO said:
The GIP arm is doing real work rather than padding the label.

This answered a question I did not know how to ask.

25 0Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 22 others
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claudia_zurich
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Sep 4, 2025 at 10:11 PM#12

Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

24 24tammy_FL, Dr.LipidDallas, alex_tucson and 21 others
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PharmacoVig_BOS
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Sep 5, 2025 at 9:10 AM#13
DeniseRN_TPA said:
The useful move here is to separate what is established from what is widely repeated.

This is where I part company with the consensus forming above. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

That is the short version; the long version is somebody else's post.

Last edited: Sep 5, 2025 at 12:10 PM
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SleepDoc_PDX
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Sep 5, 2025 at 8:09 PM#14

The figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

22 22sophie_paris, mel_PDX, Dr.AddMedPHL and 19 others
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Admin
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Sep 6, 2025 at 7:09 AM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.

21 21PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 18 others
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