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ForumsCompounding & FormulationBacteriostatic water sourcing and sterility considerations — July 2024 Page 6

Bacteriostatic water sourcing and sterility considerations — July 2024

Dr.GastroMayo Tue, Dec 17, 2024 at 10:11 AM 48 replies 2,414 viewsPage 6 of 10
Dr.LeslieOBGYN
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May 2024
Dallas, TX
Feb 26, 2025 at 3:41 PM#26

One thing that is still open after NurseKim_ATL’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

39 14Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 36 others
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steph_laguna
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Nov 2024
Laguna Beach, CA
Mar 7, 2025 at 7:25 PM#27
kate.chem said:
Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

Bacteriostatic water quality matters for dosing arithmetic reconstitution. Not all BAC water is created equal:

  • Should contain 0.9% benzyl alcohol as preservative
  • Must be sterile and pyrogen-free
  • Should come in a sealed, intact vial
  • Check expiration date — yes, BAC water expires
  • Store at room temperature, protected from light

I buy from a reputable medical supply company, not Amazon marketplace sellers. The $3 savings isn't worth the infection risk from unverified BAC water.

Last edited: Mar 8, 2025 at 1:25 AM
38 13GraceAZ_72, carl_compliance, DanielChem_CHI and 35 others
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Dr.BariatricHTX
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Mar 16, 2025 at 11:15 PM#28
kate.chem said:
Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

Agreed, with a caveat about community reputation: it is a lagging indicator. Reports arrive weeks after orders, so a supplier can look excellent for a month after quality has already changed.

37 12Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 34 others
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hank_denver
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Sep 2024
Denver, CO
Mar 26, 2025 at 3:10 AM#29
kate.chem said:
Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.

36 11fiona_VT, denise_HTX, raj_cambridge and 33 others
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Dr.GastroMayo
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Mayo Clinic, MN
Apr 4, 2025 at 7:10 AM#30

Reporting back.

Went back through my own correspondence with an earlier supplier and the warning signs were all there in the replies, weeks before the quality changed. I was reading the product and not the behaviour.

14 14InsuranceTom, WendyG_ATL, SaraMom3 and 11 others
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