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ForumsPublic SquarePCOS and GLP-1 agonists — my results so far

PCOS and GLP-1 agonists — my results so far

ingrid_STO Sun, Mar 16, 2025 at 6:04 AM 29 replies 1,996 viewsPage 1 of 6
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ingrid_STO
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Stockholm, SE
Mar 16, 2025 at 6:04 AM#1

Started this for PCOS-related insulin resistance, and the thing nobody prepared me for was that my cycle came back within two months.

The bit I cannot resolve on my own is what the washout thinking is before trying to conceive, and why nobody mentions that fertility often increases as a side effect.

Happy to be told the question itself is wrong.

11 14VendorMark, COA_Karl, MikeFit_NJ and 8 others
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RetaRick_CA
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Mar 16, 2025 at 6:40 AM#2
ingrid_STO said:
Started this for PCOS-related insulin resistance, and the thing nobody prepared me for was that my cycle came back within two months.
ingrid_STO said:
...everyone should be on fertility and pregnancy...

I understand the enthusiasm, but "everyone" is too broad. Contraindications exist: personal/family history of MTC or MEN2, history of pancreatitis, pregnancy/breastfeeding, and certain GI conditions.

Beyond contraindications, clinical judgment matters. A 22-year-old with BMI 28 and no comorbidities has a different risk-benefit calculation than a 55-year-old with BMI 38 and metabolic syndrome.

Let's advocate for ACCESS without advocating for UNIVERSAL use. They're different things.

Last edited: Mar 16, 2025 at 7:40 AM
12 15AmyNC_wife, SkepticalSean, Dr.CardioMD and 9 others
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VanRx_Mike
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Mar 16, 2025 at 7:15 AM#3
RetaRick_CA said:
ingrid_STO said: ...everyone should be on fertility and pregnancy...

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

13 16Admin, Dr.Martinez, mike_mod and 10 others
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stefan_berlin
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Oct 2024
Berlin, DE
Mar 16, 2025 at 7:50 AM#4
ingrid_STO said:
Started this for PCOS-related insulin resistance, and the thing nobody prepared me for was that my cycle came back within two months.

This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.

14 17TirzTom, TrialTracker_MD, JennaRN and 11 others
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Dr.GastroMayo
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Mar 16, 2025 at 11:07 AM#5

From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

15 18InsuranceTom, WendyG_ATL, SaraMom3 and 12 others
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