Dr.ObesityLA said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.
LondonLisa said:The mechanism is more central than most summaries suggest.
Saving this. It is the first explanation that did not require me to already understand it. Sending this to two other people who asked me the same thing last week.
Dr.ObesityLA said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
I read this differently from Dr.ObesityLA, on substance rather than tone. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.
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View ResultsThe figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Report rather than reply if it drifts again.