PedsEndoPhilly said:The useful move here is to separate what is established from what is widely repeated.
That holds for the injectable. The oral formulation has different absorption behaviour and the dose numbers are not interchangeable, which is worth saying out loud because people quote them as if they were.
Dr.MetabolicMD said:The mechanism that matters here is not stomach emptying, it is central.
Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.
PedsEndoPhilly said:The useful move here is to separate what is established from what is widely repeated.
I read this differently from PedsEndoPhilly, on substance rather than tone. The trial means are being read too generously in this thread. STEP populations were selected, supported, and titrated by protocol, and the real-world curves are consistently a few points worse. That difference is not noise, it is what happens when you remove the study infrastructure.
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View ResultsThe figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.