Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
One thing that is still open after claudia_zurich’s answer:
Was that from a primary source or from a summary of one?
TrialTracker_MD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Pushing back on TrialTracker_MD here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.
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Shop Reference StandardsTrialTracker_MD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Thread quality here is what the rules are for. Keep it up.