🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareHair loss on GLP-1 agonists: telogen effluvium vs nutritional deficiency — 6 month update

Hair loss on GLP-1 agonists: telogen effluvium vs nutritional deficiency — 6 month update

TrialTracker_MD Tue, Nov 11, 2025 at 4:36 PM 23 replies 1,449 viewsPage 1 of 5
This thread is more than 6 months old. Information may be outdated. Consider searching for more recent discussions.
TrialTracker_MD
Senior Member
2,345
15,678
Jan 2024
Maryland
Nov 11, 2025 at 4:36 PM#1

Read the primary source rather than the write-up and the two do not agree, so here is what is actually in it.

This is telogen effluvium and the trigger is the rate of weight loss rather than the molecule. Rapid loss pushes a large fraction of follicles into the resting phase simultaneously; they shed together two to four months later, which is why the shedding starts long after the loss did and why people misattribute the timing. It is self-limiting, and regrowth follows once the rate slows — the follicles are not damaged.

Where I think it is weakest: the comparator does most of the work in how this gets reported, and it is not the comparator most people think they are citing.

What I am after is whether the shedding is the drug or the rate of loss, and when it stops. Tell me what I have not thought of.

Note on sourcing:
Figures above are from the primary publication rather than the press summary. If a number here disagrees with one you have, post yours and we will work out which of us is reading a secondary source.
19 14Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 16 others
Reply Quote Save Share Report
Dr.LipidDallas
VIP Member
2,678
14,567
Dec 2023
Dallas, TX
Nov 11, 2025 at 4:59 PM#2
TrialTracker_MD said:
This is telogen effluvium and the trigger is the rate of weight loss rather than the molecule.

Agreed, with the caveat that iron should be tested before supplementing, not after. Supplementing iron into normal stores is unpleasant at best and harmful in haemochromatosis.

Last edited: Nov 11, 2025 at 6:59 PM
18 13wei_SG, cory_ATX, lori_vegas and 15 others
Reply Quote Save Share Report
sarah.morrison
VIP Member
3,212
14,567
Jan 2024
California
Online
Nov 11, 2025 at 5:22 PM#3
TrialTracker_MD said:
This is telogen effluvium and the trigger is the rate of weight loss rather than the molecule.

Hair loss update related to hair shedding: I experienced noticeable shedding starting around month 5. My dermatologist confirmed it's telogen effluvium — a stress response to rapid weight loss, NOT the medication directly.

What's helping:

  • Biotin 5000mcg daily
  • Adequate protein (130g+/day)
  • Iron and ferritin levels checked and supplemented
  • Collagen peptides 20g daily
  • Minoxidil 5% topical (prescribed)

The shedding slowed after 2 months and my hair is now growing back. Temporary but definitely stressful.

Last edited: Nov 11, 2025 at 6:22 PM
17 12tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 14 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
andrew_nyc
Member
534
2,345
Apr 2024
New York, NY
Nov 11, 2025 at 5:45 PM#4

This one has a reasonably settled answer, so here it is. A sustained drop to 1,100 or 1,200 calories reliably under-delivers a predictable set: B12, vitamin D, iron, folate, zinc and magnesium. Two of those are worth testing rather than guessing because the tests are cheap and the symptoms overlap with everything else — ferritin and B12. The rest a decent multivitamin covers, and there is no benefit in megadosing any of them.

16 11julia.endo, JessicaM_2024, TomFromTexas and 13 others
Reply Quote Save Share Report
FranDenver
Member
267
1,123
Oct 2024
Denver, CO
Nov 11, 2025 at 7:52 PM#5
Dr.LipidDallas said:
Agreed, with the caveat that iron should be tested before supplementing, not after.

Same experience, arrived at from the opposite direction. The detail I would add is minor and it is already implied above.

15 10GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 12 others
Reply Quote Save Share Report
1235

Similar Threads

SELECT trial 4-year follow-up data released — sustained MACE reduction16 replies
GLP-1 receptor agonists and thyroid C-cell concerns — evidence review19 replies
Is there a ceiling effect for GLP-1-mediated weight loss?20 replies
Comparative pharmacokinetics: semaglutide vs tirzepatide vs retatrutide6 replies
My 18-month semaglutide journey — comprehensive data log20 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register