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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralSleep quality changes on GLP-1 — my results so far Page 2

Sleep quality changes on GLP-1 — my results so far

ricardo_MIA Mon, Dec 15, 2025 at 6:52 AM 41 replies 1,867 viewsPage 2 of 9
julia.endo
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Dec 15, 2025 at 11:28 AM#6
BethLabQueen said:
When to call your doctor about mental health side effects — a reference I wish I'd had: Call immediately: Severe abdominal pain (could be…

I read this differently from BethLabQueen, on substance rather than tone. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.

12 7anna.melb_AU, mark_tokyo, hans_munich and 9 others
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quinn_sf
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Dec 15, 2025 at 1:16 PM#7
ricardo_MIA said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

11 6Dr.PathRoch, mona_PHX, andrew_nyc and 8 others
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Dr.PathRoch
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Dec 15, 2025 at 3:04 PM#8
julia.endo said:
I would be careful about how confidently the flatness reports get attributed.

Therapy insights from my mental health journey: my therapist introduced me to the concept of "identity updating" — the psychological work of becoming a new version of yourself.

Key realizations: I used food to manage emotions, I had internalized fatphobia that I'm still unpacking, my social identity was partly built around being "the big guy/girl," and learning to accept compliments is surprisingly hard when you've been invisible for years.

Physical transformation without emotional processing is unstable. Do both.

Last edited: Dec 15, 2025 at 9:04 PM
10 5WendyG_ATL, SaraMom3, Dr.MetabolicMD and 7 others
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jason_paloalto
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Dec 15, 2025 at 4:52 PM#9

Following on from Dr.LipidDallas — and this may be the naive question:

Was that from a primary source or from a summary of one?

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ricardo_MIA
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Dec 16, 2025 at 1:33 AM#10

OP back with an update, since a thread like this is useless without one.

Update: I got the sleep and the intake sorted before deciding it was the drug, and most of the flatness went with them. Not all of it, and I am watching the rest.

Last edited: Dec 16, 2025 at 6:33 AM
49 22ChrisMacros, KetoKyle, CanadaChris and 46 others
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