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ForumsOral GLP-1 AgonistsOral GLP-1 adherence — 12 month update Page 3

Oral GLP-1 adherence — 12 month update

patPC_UT Tue, Dec 17, 2024 at 11:10 AM 46 replies 2,424 viewsPage 3 of 10
HPLC_Greg
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Dec 22, 2024 at 12:01 PM#11
BariatricNurseD said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

10 8SallyK_inj, CryptoCarl, MariaRD and 7 others
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B12Beth
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Dec 22, 2024 at 3:26 PM#12
MaxMetOK said:
The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest.

This is exactly what I could not find anywhere else.

11 9carl_compliance, DanielChem_CHI, marco_milano and 8 others
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RegAffairsDC
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Dec 22, 2024 at 6:51 PM#13
BariatricNurseD said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

12 10hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 9 others
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jason_paloalto
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Dec 22, 2024 at 10:16 PM#14

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

Last edited: Dec 23, 2024 at 3:16 AM
13 11andrew_nyc, Dr.EndoEP, GraceAZ_72 and 10 others
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mike_mod
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Dec 23, 2024 at 1:41 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Tagging this one for the weekly digest.

Last edited: Dec 23, 2024 at 3:41 AM
14 12PurityPaulOR, MaxMetOK, MounjBrad and 11 others
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