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ForumsPublic SquareGLP-1 therapy in patients over 65 — safety and efficacy data

GLP-1 therapy in patients over 65 — safety and efficacy data

GraceAZ_72 Sun, Apr 5, 2026 at 11:59 AM 40 replies 1,293 viewsPage 1 of 8
GraceAZ_72
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Apr 5, 2026 at 11:59 AM#1

The weight came off and the harder part started, which is not what any of the material I read had prepared me for.

The bit I cannot resolve on my own is how people separated a drug effect from the ordinary consequences of a large deficit and disrupted sleep, because I cannot.

If the honest answer is that nobody knows, that is a useful answer and I would rather have it.

40 10MariaRD, AussieAnna, BethLabQueen and 37 others
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PurityPaulOR
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Apr 5, 2026 at 12:44 PM#2
GraceAZ_72 said:
The weight came off and the harder part started, which is not what any of the material I read had prepared me for.
GraceAZ_72 said:
...mental health should only be used alongside therapy...

I'd say therapy should be AVAILABLE to all GLP-1 patients, but requiring it as a precondition for treatment would create an access barrier.

Not everyone can afford therapy. Not everyone needs it. Some people do just fine with medication + lifestyle changes. But for those with emotional eating, body image issues, or disordered eating history, therapy is extremely valuable.

My recommendation: make mental health screening part of the initial assessment, offer therapy as a recommended adjunct, but don't gatekeep medication access behind it.

39 9MikeNYC_runner and 36 others
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LibrarianMeg
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Apr 5, 2026 at 1:30 PM#3
PurityPaulOR said:
GraceAZ_72 said: ...mental health should only be used alongside therapy...

Body image adjustment with mental health: I've lost 55 lbs but when I look in the mirror, I still see my old self sometimes. "Phantom fat" is a real phenomenon.

My therapist specializes in body image issues with weight loss patients. She says it can take 12-18 months for your brain's body map to update. In the meantime: take progress photos (your eyes lie but cameras don't), try on old clothes, and be patient with yourself.

Last edited: Apr 5, 2026 at 3:30 PM
38 8julia.endo, JessicaM_2024, TomFromTexas and 35 others
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sarah_nash92
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Apr 5, 2026 at 2:16 PM#4
GraceAZ_72 said:
The weight came off and the harder part started, which is not what any of the material I read had prepared me for.

Same pattern here, and in the same order.

Last edited: Apr 5, 2026 at 8:16 PM
37 7CanadaChris, ZaraB_AL, JakeSmashed95 and 34 others
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PharmD_Rodriguez
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Apr 5, 2026 at 6:32 PM#5

From the other side of the consultation, briefly.

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about loose skin.

This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.

Last edited: Apr 5, 2026 at 11:32 PM
36 6MeganSA_TX, LarryQC_SD, wanda_boise and 33 others
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