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ForumsCompounding & FormulationCompounded peptide reconstitution water — BAC vs sterile water comparison Page 2

Compounded peptide reconstitution water — BAC vs sterile water comparison

CarlaRPh_TPA Thu, Jun 4, 2026 at 6:29 AM 6 replies 211 viewsPage 2 of 2
PeptideChemSF
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Jun 4, 2026 at 9:41 AM#6

Adding the numbers, since they settle part of this. Two things anyone can check: a state licence number for a 503A, and an FDA outsourcing-facility registration for a 503B. Both are publicly searchable, and a pharmacy unwilling to give you either has answered the question.

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GraceAZ_72
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Jun 4, 2026 at 10:56 AM#7

A narrower follow-up, since the general answer is now clear:

How much material I am losing to dead space, and whether that explains why a 10mg vial gives me nine usable draws rather than ten?

Last edited: Jun 4, 2026 at 2:56 PM
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anders_CPH
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Jun 4, 2026 at 12:11 PM#8
PeptideChemSF said:
Two things anyone can check: a state licence number for a 503A, and an FDA outsourcing-facility registration for a 503B.

Adding the part of the answer the thread has not reached. Resolution therefore closed the doors unevenly, and the asymmetry follows from the bulks lists. For 503B the shortage clause was the only route to these molecules, so that route shut completely. A 503A pharmacy can still argue a doorway via "component of an approved drug" — but only for the substance in the form present in the approved product, which is exactly where the base-versus-salt argument lives, and it does nothing about the copy restriction, which came back into force on resolution.

That is the short version; the long version is somebody else's post.

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CarlaRPh_TPA
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Jun 4, 2026 at 1:26 PM#9

OP back with an update, since a thread like this is useless without one.

Resolved. I wrote mg, ml and mg/ml on the vial in marker and did the division in that order, and the two of us now get the same number every time.

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SarahChen_PharmD
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Jun 4, 2026 at 7:26 PM#10
anders_CPH said:
Resolution therefore closed the doors unevenly, and the asymmetry follows from the bulks lists.

No disagreement with anders_CPH. One condition attached. The arithmetic is right and one caveat matters: a U-40 syringe changes the markings, not the volumes. If someone hands you U-40 and you read it as U-100 you will be 2.5 times out, and that error has a direction — it is always an overdose.

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