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ForumsOff-TopicHas anyone dealt with road trip snack guide?

Has anyone dealt with road trip snack guide?

LabKate Thu, Feb 22, 2024 at 9:34 AM 16 replies 2,253 viewsPage 1 of 4
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LabKate
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Feb 22, 2024 at 9:34 AM#1

The thing that changed for me was not hunger, it was that the constant background negotiation about food simply stopped, and I had not realised it was constant until it was not.

What I am after is whether the quiet is the same mechanism as the appetite suppression or a separate one, because they seem to come and go on different schedules.

If the honest answer is that nobody knows, that is a useful answer and I would rather have it.

36 6JenMemphis, pat_auckland, Dr.GastroMayo and 33 others
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Dr.CardioMD
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Feb 22, 2024 at 9:47 AM#2
LabKate said:
The thing that changed for me was not hunger, it was that the constant background negotiation about food simply stopped, and I had not realised it was…

Alcohol relationship change with food noise: I used to drink 3-4 beers most nights. Since starting GLP-1 therapy, I have zero interest in alcohol. Haven't had a drink in 6 months.

The "food noise" reduction seems to extend to other reward-seeking behaviors, including alcohol. My liver enzymes have improved, my sleep is better, and I've saved roughly $156/month on alcohol. Triple win.

35 5Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 32 others
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MikeNYC_runner
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Feb 22, 2024 at 10:00 AM#3
Dr.CardioMD said:
Alcohol relationship change with food noise: I used to drink 3-4 beers most nights.

"Food aversion" side effect of food noise that I wasn't prepared for: I used to LOVE cooking and trying new restaurants. Now certain foods — especially red meat — literally repulse me.

It's not just reduced appetite; it's an active disgust response. My therapist says this is common and likely related to the reward pathway modulation. It's mostly a positive change, but I do miss enjoying food the way I used to.

34 4Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 31 others
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DadBodDave
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Feb 22, 2024 at 10:13 AM#4
LabKate said:
The thing that changed for me was not hunger, it was that the constant background negotiation about food simply stopped, and I had not realised it was…

Mine went the same way, slower. The detail I would add is minor and it is already implied above.

Last edited: Feb 22, 2024 at 1:13 PM
33 3Dr.GastroMayo, JakeBK_lifts, DerekSJ_a1c and 30 others
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james_edin
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Feb 22, 2024 at 11:19 AM#5

Clinical perspective, offered as context rather than as advice.

The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related hospitalizations in GLP-1 agonist users[1].

The mechanism is plausible: GLP-1R is expressed in the mesolimbic reward pathway (VTA, nucleus accumbens). Agonism at these receptors may reduce the reinforcing properties of alcohol, similar to the reduction in "food noise."

RCTs for GLP-1 agonists in AUD are now underway. If positive, this would be a paradigm-shifting repurposing of existing medications.

References:
[1] Wang W, et al. Nat Med. 2024;30:574-584.
Last edited: Feb 22, 2024 at 1:19 PM
32 2bbq_ray_KC, oliver_london, tane_welly and 29 others
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