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ForumsOral GLP-1 AgonistsIs oral sema actually as effective as the injection version? — 12 month update Page 7

Is oral sema actually as effective as the injection version? — 12 month update

tommy_boulder Tue, Dec 16, 2025 at 3:17 AM 35 replies 1,548 viewsPage 7 of 7
newstart_MO
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Jan 22, 2026 at 6:59 AM#31

From the other side of the consultation, briefly. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

Last edited: Jan 22, 2026 at 12:59 PM
2 2bri_stats, pete_manc_UK
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LeilaHI
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Jan 2025
Honolulu, HI
Jan 25, 2026 at 4:03 AM#32
newstart_MO said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Second this.

1 1VendorMark
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andrew_nyc
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Apr 2024
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Jan 28, 2026 at 1:09 AM#33
newstart_MO said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

There is a second half to this that has not been said yet. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

50 0PharmD_Rodriguez, julia.endo, JessicaM_2024 and 47 others
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DataDave
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Jan 30, 2026 at 10:17 PM#34

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

49 24amsterdam_pete, LondonLisa, mike_nyc and 46 others
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BrianDallas92
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Oct 2024
Dallas, TX
Feb 2, 2026 at 7:26 PM#35

Following on from newstart_MO — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

48 23GraceAZ_72, carl_compliance, DanielChem_CHI and 45 others
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