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ForumsOff-TopicWater bottle recommendations — anyone have experience? Page 2

Water bottle recommendations — anyone have experience?

LipidDoc_ATL Thu, Jan 9, 2025 at 1:33 PM 11 replies 1,681 viewsPage 2 of 3
hank_denver
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Jan 9, 2025 at 7:16 PM#6
LipidDoc_ATL said:
Food noise is the best term this community has produced and it describes something the trials did not measure well: the constant background…

The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related hospitalizations in GLP-1 agonist users[1].

The mechanism is plausible: GLP-1R is expressed in the mesolimbic reward pathway (VTA, nucleus accumbens). Agonism at these receptors may reduce the reinforcing properties of alcohol, similar to the reduction in "food noise."

RCTs for GLP-1 agonists in AUD are now underway. If positive, this would be a paradigm-shifting repurposing of existing medications.

References:
[1] Wang W, et al. Nat Med. 2024;30:574-584.
7 2ingrid_STO, pete_nash, hank_denver and 4 others
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KetoKyle
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Jul 2024
Utah
Jan 9, 2025 at 9:30 PM#7

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

Last edited: Jan 9, 2025 at 10:30 PM
6 1JenMemphis, pat_auckland, Dr.GastroMayo and 3 others
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Dr.NutriCornell
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Jan 9, 2025 at 11:44 PM#8
hank_denver said:
The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related…

Rebound hunger after missed dose of food noise: I missed my injection by 3 days due to a shipping delay and the hunger came ROARING back. Like a switch flipped. It was eye-opening to feel the difference.

This experience actually reinforced my understanding of what the medication does — it's not just "suppressing appetite," it's normalizing dysregulated hunger signaling. When the drug wears off, you feel the full force of what it was managing.

5 0laura_annarbor, JenMemphis, pat_auckland and 2 others
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LipidDoc_ATL
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Apr 2024
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Jan 10, 2025 at 1:58 AM#9
hank_denver said:
The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related…

"Food aversion" side effect of food noise that I wasn't prepared for: I used to LOVE cooking and trying new restaurants. Now certain foods — especially heavy cream sauces — literally repulse me.

It's not just reduced appetite; it's an active disgust response. My therapist says this is common and likely related to the reward pathway modulation. It's mostly a positive change, but I do miss enjoying food the way I used to.

Last edited: Jan 10, 2025 at 6:58 AM
4 24DebRD_ATL, KristenIndy, MarkLI_maint and 1 other
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SallyK_inj
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Jan 10, 2025 at 12:43 PM#10
Dr.NutriCornell said:
Rebound hunger after missed dose of food noise: I missed my injection by 3 days due to a shipping delay and the hunger came ROARING back.

Phantom hunger vs real hunger on food noise: learning to distinguish between the two has been a revelation. Real hunger: gradual onset, physical stomach sensation, any food sounds good. Phantom hunger: sudden, emotionally triggered, specific food cravings, occurs right after eating.

The GLP-1 agonist suppresses real hunger beautifully. Phantom hunger still pops up but I can now recognize it for what it is — an emotional signal, not a physical need. Mindfulness training helped enormously with this distinction.

48 23Dr.PathRoch, mona_PHX, andrew_nyc and 45 others
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