dan_philly said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Genuinely useful, thank you. I had the facts and not the framework.
Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
DeniseRN_TPA said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Mine went the same way, slower. I had assumed I was the exception until I read this.
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View ResultsDeniseRN_TPA said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
There is a second half to this that has not been said yet. The gap between trial results and real-world results is consistent and it is not fraud. Trial participants get titration by protocol, scheduled contact, free drug and dietetic support; removing that infrastructure costs a few percentage points every time it has been measured. When your own curve sits below the published mean, that is the likeliest explanation before anything about you or your material.
I would rather be corrected than agreed with, if it comes to it.
OP back with an update, since a thread like this is useless without one.
Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.