Peptide degradation pathways — what worked for you?

Dr.LipidDallas said:

PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

NurseLeah_Nash said:

The pharmacokinetics explain nearly every practical question asked here.

This answered a question I did not know how to ask. Adding it to my notes with a link back to this thread.

Dr.LipidDallas said:

PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.