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ForumsPharmacology & MechanismsSemaglutide fatty acid sidechain — 12 month update Page 5

Semaglutide fatty acid sidechain — 12 month update

SaraMom3 Wed, Sep 11, 2024 at 3:09 PM 36 replies 2,367 viewsPage 5 of 8
sean_dublin
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Sep 19, 2024 at 6:32 PM#21
VendorMark said:
The dose-response is real but shallow at the top.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

25 23hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 22 others
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kevin_tulsa
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Sep 20, 2024 at 7:20 AM#22
VendorMark said:
The dose-response is real but shallow at the top.

This answered a question I did not know how to ask.

26 24Dr.RheumBOS, greg_boulder, quinn_sf and 23 others
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Dr.EndoEP
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Sep 20, 2024 at 8:07 PM#23

From the other side of the consultation, briefly. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

27 0FranDenver, Dr.BariatricHTX, LindaRN_retired and 24 others
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DeniseRN_TPA
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Sep 21, 2024 at 8:54 AM#24
Dr.EndoEP said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

This matches mine closely enough to be worth saying so out loud. The detail I would add is minor and it is already implied above.

28 1LindaRN_retired, tommy_boulder, hyun_seoul and 25 others
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hans_munich
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Sep 21, 2024 at 9:41 PM#25
Dr.EndoEP said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Adding the part of the answer the thread has not reached. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: Sep 22, 2024 at 3:41 AM
29 2emma_london, tammy_FL, Dr.LipidDallas and 26 others
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