The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
That is the short version; the long version is somebody else's post.
A narrower follow-up, since the general answer is now clear:
Whether the fasting requirement is as strict in practice as the label implies, and what people actually see when they get it wrong?
BiostatsBrad said:If you are going to change something, change one thing and give it long enough to express itself.
Coming at BiostatsBrad’s question from a different direction. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.
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View ResultsClosing the loop on my own question.
I moved the tablet to the moment I wake up rather than trying to fit it around breakfast, and the difference in the following weeks was obvious. It was a timing problem, not a dose problem.
TrialNerd_Beth said:The useful move here is to separate what is established from what is widely repeated.
TrialNerd_Beth has the substance of this right. The condition it depends on is worth stating. The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest. Where it bites is in the first fortnight, when people conclude the tablet does nothing.