One thing that is still open after sarah_TO’s answer:
How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?
jason_paloalto said:One habit that pays for itself: post the method alongside the number.
I read this differently from jason_paloalto, on substance rather than tone. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.
jason_paloalto said:One habit that pays for itself: post the method alongside the number.
Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
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View Resultsjason_paloalto said:One habit that pays for itself: post the method alongside the number.
This is exactly what I could not find anywhere else.
OP back with an update, since a thread like this is useless without one.
Update. I did go to 2.4mg in the end, and the honest report is that it bought me less than the step before it and cost me two bad weeks. Worth knowing rather than worth repeating.