Enteroendocrine L-cell biology — 12 month update

Dr.BariatricHTX said:

Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

I read this differently from Dr.BariatricHTX, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Dr.BariatricHTX said:

Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

Dr.BariatricHTX said:

Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

From the other side of the consultation, briefly. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

DeniseRN_TPA said:

Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Same pattern here, and in the same order.