james_edin said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
carl_compliance said:The pharmacokinetics explain nearly every practical question asked here.
Thank you — that is the clearest version of this I have read, and I have read a lot of them. Printing the relevant bit and taking it with me.
james_edin said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Pushing back on james_edin here. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.
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View ResultsAdding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
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