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ForumsDosing & ProtocolsReconstitution calculator — what worked for you? Page 4

Reconstitution calculator — what worked for you?

PharmD_Rodriguez Tue, Jan 9, 2024 at 11:57 PM 18 replies 2,217 viewsPage 4 of 4
Dr.BariatricHTX
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Jan 14, 2024 at 11:50 AM#16

From the other side of the consultation, briefly.

Ongoing cost tracking for dosing arithmetic — transparency for the community:

Monthly medication cost: $132
Supplies (syringes, BAC water, alcohol swabs): ~$10/month
Janoshik testing: ~$12/month (amortized quarterly)
Lab work: ~$42/month (amortized quarterly)
Total: ~$222/month

Compare to brand Wegovy at $1322/month without insurance. Compounded is roughly 90% cheaper for what I have found to be clinically equivalent medication.

Last edited: Jan 14, 2024 at 5:50 PM
47 20CarlaRPh_TPA, steph_laguna, fiona_glasgow and 44 others
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VanRx_Mike
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Jan 14, 2024 at 11:16 PM#17

From the other side of the consultation, briefly.

Comparison of compounded dosing arithmetic delivery formats I've tried:

FormatProsCons
Lyophilized vialLongest shelf life, lowest costRequires reconstitution
Pre-mixed vialReady to draw upShorter shelf life (28-45 days)
Pre-filled syringesMost convenientHigher cost, shorter shelf life
Sublingual dropsNo needlesLower bioavailability, less data

I use lyophilized vials for cost and stability. The reconstitution takes 30 seconds once you've done it a few times.

Last edited: Jan 15, 2024 at 2:16 AM
48 21MikeNYC_runner and 45 others
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KevinCompounds
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Jan 15, 2024 at 10:42 AM#18
VanRx_Mike said:
Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

Same pattern here, and in the same order. Posting only so the count is not one.

Last edited: Jan 15, 2024 at 12:42 PM
49 22MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 46 others
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Dr.PeteFamMed
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Jan 15, 2024 at 10:08 PM#19
VanRx_Mike said:
Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

Compounding pharmacy dose accuracy check for dosing arithmetic: I always verify my first dose from a new vial by weighing it on a milligram scale. Draw up your dose, weigh the syringe, subtract empty syringe weight, compare to expected water weight at that volume.

For a 10-unit dose (0.1mL): expected weight ~100mg of water. If it's significantly off, your syringe may be inaccurate. Cheap insulin syringes can have ±5% volume accuracy. Spring for quality brands like BD or Terumo.

50 23Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 47 others
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Admin
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Jan 16, 2024 at 9:34 AM#20

Moderator note: a couple of off-topic posts removed.

Last edited: Jan 16, 2024 at 1:34 PM
22 20PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 19 others
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