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ForumsDosing & ProtocolsOops I think I injected into muscle - panicking — need advice

Oops I think I injected into muscle - panicking — need advice

sarah_TO Wed, Jun 12, 2024 at 10:29 AM 12 replies 2,112 viewsPage 1 of 3
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sarah_TO
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Jun 12, 2024 at 10:29 AM#1

Two DEXA scans eleven months apart: down 24kg total, of which the scan says 6kg was lean. I want to know whether that ratio is bad, normal, or simply what happens.

What I am trying to establish is whether resistance training and protein change the ratio or only the absolute amount.

If the honest answer is that nobody knows, that is a useful answer and I would rather have it.

7 2andrew_nyc, Dr.EndoEP, GraceAZ_72 and 4 others
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Dr.KarenChen
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Jun 12, 2024 at 12:15 PM#2

Short answer first, then the reasoning. The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0 g/kg of reference body weight, and not making the deficit larger than the training can support. Cardio does not protect lean mass and in a deep deficit competes with recovery.

6 1JessicaM_2024, TomFromTexas, mike.trainer_LA and 3 others
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Dr.EndoEP
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Jun 12, 2024 at 2:02 PM#3
Dr.KarenChen said:
The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0…

Agreed on the ranges, with the condition that a single DEXA is not a measurement, it is one draw from a distribution. Hydration status moves the lean compartment by a kilogram or more between scans, so any comparison of scans done at different times of day or different hydration states is noise.

5 0FranDenver, Dr.BariatricHTX, LindaRN_retired and 2 others
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DeniseRN_TPA
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Jun 12, 2024 at 3:49 PM#4
sarah_TO said:
Two DEXA scans eleven months apart: down 24kg total, of which the scan says 6kg was lean.

This matches mine closely enough to be worth saying so. The honest range is roughly 20 to 40% of total loss as lean mass without deliberate resistance training, and roughly 10 to 20% with it plus adequate protein. Both numbers need a caveat that matters: "lean mass" on a DEXA is not muscle. It includes water, glycogen and the lean fraction of organs, and glycogen alone carries about three grams of water per gram. A large early lean drop is mostly the glycogen and water going, which is why the first scan flatters and the second is the honest one.

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Dr.Martinez
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Jun 13, 2024 at 2:17 AM#5

From the other side of the consultation, briefly.

DEXA scan update relevant to lean mass:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass266 lbs236 lbs193 lbs
Fat mass96 lbs66 lbs43 lbs
Lean mass149 lbs145 lbs150 lbs
Body fat %43%31%22%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The lean mass discussion needs to include body comp data, not just scale weight.

3 23adam_van, Dr.SurgeonPGH, rachel_ABQ
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