Adiponectin and leptin changes on GLP-1 therapy — what worked for you?

bri_stats said:

The weight came off and the harder part started, which is not what any of the material I read had prepared me for.

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about whether I deserved to feel good.

This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.

kate.chem said:

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me.

Positive side effects of mental health that surprised me:

1. Clearer skin — inflammation reduction improved my rosacea
2. Better sleep — weight loss resolved mild sleep apnea
3. Improved libido — better body image + improved cardiovascular health
4. Less joint pain — obvious mechanical benefit
5. More energy — metabolic improvements across the board

Not everything about GLP-1 therapy is a struggle. There are genuinely wonderful changes too. ✨

bri_stats said:

The weight came off and the harder part started, which is not what any of the material I read had prepared me for.

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

From the other side of the consultation, briefly.

One year anniversary on mental health — reflections:

What I wish I'd known: the side effects are temporary, the benefits compound over time, protein is more important than I thought, and the mental health aspect needs as much attention as the physical.

What surprised me: how much my relationship with food changed, the cascade of health improvements beyond weight, and how supportive this community is.

What I'd do differently: start therapy earlier, prioritize resistance training from day 1, and stop comparing my progress to others. Everyone's journey is unique.