Has anyone dealt with so the drug literally changes your brain?? that is wild?

Dr.NephBHM_UK said:

Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

Genuinely useful, thank you. I had the facts and not the framework. I will report back once I have actually tried it.

Clinical perspective, offered as context rather than as advice. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

roxy_nash said:

Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).

Pushing back on roxy_nash here. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

I would rather be corrected than agreed with, if it comes to it.

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.