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ForumsDosing & ProtocolsAir bubbles in syringe — 12 month update Page 6

Air bubbles in syringe — 12 month update

fiona_glasgow Wed, Sep 11, 2024 at 12:21 PM 48 replies 2,979 viewsPage 6 of 10
Dr.AddMedPHL
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Oct 23, 2024 at 8:33 PM#26

Clinical perspective, offered as context rather than as advice.

Comparison of compounded dosing arithmetic delivery formats I've tried:

FormatProsCons
Lyophilized vialLongest shelf life, lowest costRequires reconstitution
Pre-mixed vialReady to draw upShorter shelf life (28-45 days)
Pre-filled syringesMost convenientHigher cost, shorter shelf life
Sublingual dropsNo needlesLower bioavailability, less data

I use lyophilized vials for cost and stability. The reconstitution takes 30 seconds once you've done it a few times.

11 9FitDadDave, RunnerRach, TrialNerd_Beth and 8 others
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jim_asheville
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Oct 29, 2024 at 10:03 AM#27
Dr.AddMedPHL said:
Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

Same pattern here, and in the same order. Posting only so the count is not one.

12 10BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 9 others
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patPC_UT
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Nov 3, 2024 at 11:36 PM#28
Dr.AddMedPHL said:
Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

Adding the part of the answer the thread has not reached. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

13 11TomFromTexas, mike.trainer_LA, sarah_nash92 and 10 others
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kate.chem
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Nov 9, 2024 at 1:12 PM#29

One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Last edited: Nov 9, 2024 at 4:12 PM
14 12jennifer_SEA, tyler_CSCS, VanRx_Mike and 11 others
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fiona_glasgow
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Nov 15, 2024 at 2:52 AM#30

Closing the loop on my own question.

Coming back a few months on. It held. Nothing dramatic to report, which is the report.

Last edited: Nov 15, 2024 at 7:52 AM
36 9NeuroNate, JessicaH_TX, KevinCompounds and 33 others
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