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ForumsPharmacology & MechanismsHas anyone dealt with glucagon receptor signaling? Page 3

Has anyone dealt with glucagon receptor signaling?

ricardo_MIA Sun, Jan 4, 2026 at 4:13 AM 20 replies 1,073 viewsPage 3 of 4
greg_boulder
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Jan 5, 2026 at 6:33 AM#11
DebRD_ATL said:
The mechanism is more central than most summaries suggest.

Bookmarking. The distinction being drawn above is the one nobody else makes. Printing the relevant bit and taking it with me.

23 21denise_HTX, raj_cambridge, ingrid_STO and 20 others
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JenPlateau
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Jan 5, 2026 at 2:53 PM#12

From the other side of the consultation, briefly. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

24 22TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 21 others
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julia.endo
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Jan 5, 2026 at 11:13 PM#13
Dr.SurgeonPGH said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

25 23hans_munich, jason_sac26, chris_chi24 and 22 others
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PharmacoVig_BOS
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Jan 6, 2026 at 7:33 AM#14

One concrete data point for the thread. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

26 24kate.chem, DataDave, Dr.GutHealth and 23 others
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mike_mod
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Jan 6, 2026 at 3:53 PM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. No action needed from anybody.

Last edited: Jan 6, 2026 at 5:53 PM
27 0PurityPaulOR, MaxMetOK, MounjBrad and 24 others
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