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ForumsBuyer BewareWhat vendors shut down in 2025? The full list is scary — what worked for you?

What vendors shut down in 2025? The full list is scary — what worked for you?

labquiet_amy Thu, Jul 3, 2025 at 6:06 AM 21 replies 1,548 viewsPage 1 of 5
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labquiet_amy
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Jul 3, 2025 at 6:06 AM#1

Read the primary source rather than the write-up and the two do not agree, so here is what is actually in it.

Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion. Synthesis, testing, and cold-chain shipping have floors. A price well under the floor means something was skipped, and the two things that get skipped are testing and content.

Where I think it is weakest: the subgroup findings are the part I trust least — with enough subgroups something is always significant, and these were not all pre-registered.

What I am after is what a vetting checklist should actually contain, as opposed to a list of things that are easy to fake. I have searched first, so if this is covered somewhere point me at it and I will read it.

Note on sourcing:
Figures above are from the primary publication rather than the press summary. If a number here disagrees with one you have, post yours and we will work out which of us is reading a secondary source.
7 2TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 4 others
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julia.endo
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Jul 3, 2025 at 6:34 AM#2
labquiet_amy said:
Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion.

That is correct as far as it goes, and here is where it stops going. The pattern that distinguishes a bad batch from an exit is behaviour rather than product. A bad batch comes with communication, a reshipment offer and a batch number. An exit comes with slower replies, pressure toward less reversible payment methods, sudden discounting, and the same reassurance repeated without any new information. The product tells you less than the correspondence does.

Last edited: Jul 3, 2025 at 12:34 PM
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DataDave
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Jul 3, 2025 at 7:02 AM#3
labquiet_amy said:
Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion.

I disagree that testing history is decisive. It tells you what a supplier did when they were being watched. Continuity of behaviour under stress — a late shipment, a failed test, a complaint — is more predictive than any run of good results.

Last edited: Jul 3, 2025 at 8:02 AM
5 0LondonLisa, mike_nyc, VendorMark and 2 others
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Dr.LeslieOBGYN
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Jul 3, 2025 at 7:30 AM#4

This one has a reasonably settled answer, so here it is. The useful checklist is about verifiability rather than presentation. Independent test results commissioned by buyers rather than by the seller, consistency across multiple batches over time rather than one flattering report, a physical address and a company registration that resolve, batch and lot numbers on the actual labelling, and a shipping practice that matches what the material needs. Everything a good-looking website provides is cheap to fake; none of the items above are.

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hans_munich
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Jul 3, 2025 at 10:04 AM#5
julia.endo said:
The pattern that distinguishes a bad batch from an exit is behaviour rather than product.

This matches mine closely enough to be worth saying so out loud.

Last edited: Jul 3, 2025 at 4:04 PM
3 23emma_london, tammy_FL, Dr.LipidDallas
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