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ForumsDosing & ProtocolsAccidentally took double dose - freaking out right now — looking for input Page 2

Accidentally took double dose - freaking out right now — looking for input

DoseLogDan Sat, Apr 5, 2025 at 5:15 PM 13 replies 1,656 viewsPage 2 of 3
dan_philly
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Jul 2024
Philadelphia, PA
Apr 6, 2025 at 1:04 AM#6
DoseLogDan said:
Four weeks is the pharmacokinetics, not caution.

Dose escalation anxiety for titration: I was terrified to move from 0.5mg to 1.0mg based on horror stories in this forum. But my actual experience? Slightly more appetite suppression, zero additional side effects.

Remember that the people posting about terrible side effects are a biased sample. Most people titrate up without drama — they just don't post about it because it's uneventful.

18 13DadBodDave, AmyNC_wife, SkepticalSean and 15 others
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alex_tucson
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May 2024
Tucson, AZ
Apr 6, 2025 at 4:09 AM#7

Following on from NurseAsh_DET — and this may be the naive question:

Why the interval is four weeks rather than two, and whether a slower ladder gets to the same place?

17 12labquiet_amy, emily_PDX, Dr.SleepRoch and 14 others
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Dr.RheumBOS
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Apr 2024
Boston, MA
Apr 6, 2025 at 7:15 AM#8
dan_philly said:
Dose escalation anxiety for titration: I was terrified to move from 0.5mg to 1.0mg based on horror stories in this forum.

PSA for titration users considering the 0.25mg starting dose: this dose is NOT intended for weight loss. It's a titration dose to let your body adjust. Don't be discouraged if you don't lose much in the first month.

The therapeutic dose for weight management starts at 1.7mg (semaglutide) or 5mg (tirzepatide). Be patient with the ramp-up.

16 11cory_ATX, lori_vegas, Dr.PulmRoch and 13 others
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DoseLogDan
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Feb 2025
Montana
Apr 6, 2025 at 10:21 AM#9

Closing the loop on my own question.

Closing this out: I held the step for six weeks rather than four and it settled without a dose change. The interval was the answer, not the dose.

Last edited: Apr 6, 2025 at 11:21 AM
15 10sophie_paris, mel_PDX, Dr.AddMedPHL and 12 others
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maya_sedona
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Sep 2024
Sedona, AZ
Apr 7, 2025 at 1:12 AM#10
Dr.RheumBOS said:
PSA for titration users considering the 0.25mg starting dose: this dose is NOT intended for weight loss.

Agreed on the arithmetic, with one condition: holding indefinitely at a dose that is not doing anything is not patience, it is a stall with a nice name. The distinction is whether appetite has changed at all at the current step.

39 12Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 36 others
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