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ForumsMetabolic Health & DiabetesIs it possible to reverse type 2 or am I dreaming

Is it possible to reverse type 2 or am I dreaming

steve_okc Mon, May 11, 2026 at 8:28 PM 13 replies 519 viewsPage 1 of 3
steve_okc
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May 11, 2026 at 8:28 PM#1

A1C went from 7.4 to 5.6 over nine months and my prescriber was more interested in the fasting insulin, which I did not expect.

Because it is glucose-dependent, this class carries a low intrinsic hypoglycaemia risk on its own — the risk arrives when it is combined with insulin or a sulfonylurea, which usually need reducing.

The bit I cannot resolve on my own is why A1C lags the way it does, and what to look at in the meantime if you want to know sooner.

I would rather have one careful answer than five confident ones.

8 3NauseaFreeNow, SteveThurs, B12Beth and 5 others
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sarah.morrison
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May 11, 2026 at 8:36 PM#2
steve_okc said:
A1C went from 7.4 to 5.6 over nine months and my prescriber was more interested in the fasting insulin, which I did not expect.

PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

After 12 months: periods became regular for the first time in ever, testosterone levels normalized, acne cleared significantly, and — unexpectedly — my hormonal symptoms have almost completely resolved.

GLP-1 agonists address the insulin resistance at the root of PCOS. For PCOS patients, this isn't "just" a weight loss drug — it's treating our underlying metabolic dysfunction.

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Dr.GastroMayo
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May 11, 2026 at 8:44 PM#3
sarah.morrison said:
PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

Insulin sensitivity test (HOMA-IR) on glycaemic control — arguably the most important metabolic marker most people aren't tracking:

HOMA-IR = (fasting insulin × fasting glucose) ÷ 405

My numbers: Baseline HOMA-IR = 5.8 (insulin resistant) → Current = 1.4 (insulin sensitive)

Anything above 2.0 indicates insulin resistance. The goal is below 1.5. GLP-1 agonists address the root metabolic dysfunction, not just the symptoms. This is why they work so much better than calorie restriction alone.

Last edited: May 12, 2026 at 1:44 AM
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wendy_avl
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May 11, 2026 at 8:52 PM#4
steve_okc said:
A1C went from 7.4 to 5.6 over nine months and my prescriber was more interested in the fasting insulin, which I did not expect.

This is my experience too, for whatever a second data point is worth. The detail I would add is minor and it is already implied above.

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TinaHashiRN
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May 11, 2026 at 9:35 PM#5

Clinical perspective, offered as context rather than as advice.

Fasting insulin is the lab my functional medicine doctor cares about most for glycaemic control: it's a much earlier marker of metabolic dysfunction than glucose or A1C.

My fasting insulin: 30 → 12 → 5 uIU/mL over 9 months. Target is <7. By the time your fasting glucose is elevated, your insulin has been elevated for YEARS trying to compensate.

Ask your doctor to include fasting insulin in your bloodwork panel. It's cheap (~$20) and incredibly informative.

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