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ForumsDosing & ProtocolsSplitting doses — 12 month update Page 3

Splitting doses — 12 month update

steph_laguna Sat, Aug 16, 2025 at 5:30 AM 24 replies 1,702 viewsPage 3 of 5
JennaRN
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Aug 17, 2025 at 12:58 AM#11
PeptideChemSF said:
The version of this that has an answer is narrower than the version being asked.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

Last edited: Aug 17, 2025 at 1:58 AM
33 8Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 30 others
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mel_PDX
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Aug 17, 2025 at 1:21 PM#12
claudia_zurich said:
Agreed, and one caution: a single measurement is not a measurement.

Thank you for spelling out the reasoning rather than just the conclusion. Adding it to my notes with a link back to this thread.

Last edited: Aug 17, 2025 at 7:21 PM
32 7Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 29 others
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mike_mod
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Aug 18, 2025 at 1:44 AM#13
PeptideChemSF said:
The version of this that has an answer is narrower than the version being asked.

This is where I part company with the consensus forming above. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

31 6DoseLogDan, SleepFixSam, PurityPaulOR and 28 others
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hank_denver
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Aug 18, 2025 at 2:06 PM#14

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Last edited: Aug 18, 2025 at 6:06 PM
30 5fiona_VT, denise_HTX, raj_cambridge and 27 others
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Admin
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Aug 19, 2025 at 2:28 AM#15

Moderator note: a couple of off-topic posts removed.

29 4PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 26 others
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