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ForumsDosing & ProtocolsDose escalation too fast? Recognizing over-titration symptoms — what worked for you? Page 3

Dose escalation too fast? Recognizing over-titration symptoms — what worked for you?

Dr.LipidDallas Sat, Oct 4, 2025 at 1:18 PM 15 replies 1,365 viewsPage 3 of 3
mike_nyc
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Oct 8, 2025 at 4:24 PM#11
PharmHunterJen said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

Last edited: Oct 8, 2025 at 8:24 PM
38 13maya_sedona, stefan_berlin, Dr.EM_Chicago and 35 others
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steve_okc
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Oct 8, 2025 at 10:32 PM#12
TrialTracker_MD said:
Agreed on the arithmetic, with one condition: holding indefinitely at a dose that is not doing anything is not patience, it is a stall with a nice…

Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.

37 12JakeSmashed95, NauseaFreeNow, SteveThurs and 34 others
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Dr.SleepRoch
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Oct 9, 2025 at 4:40 AM#13
PharmHunterJen said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

This is where I part company with the consensus forming above. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

That is the short version; the long version is somebody else's post.

Last edited: Oct 9, 2025 at 8:40 AM
36 11Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 33 others
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Dr.GutHealth
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Oct 9, 2025 at 10:48 AM#14

One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Last edited: Oct 9, 2025 at 3:48 PM
35 10Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 32 others
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Admin
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Oct 9, 2025 at 4:55 PM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Tagging this one for the weekly digest.

Last edited: Oct 9, 2025 at 8:55 PM
34 9PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 31 others
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