Peptide Sciences quality was declining BEFORE shutdown — PeptideMeter data

Adding the clinical framing, because it changes how the question reads.

COA red flags for certificates of analysis — here's what to look for when reviewing a Certificate of Analysis:

• No HPLC data: If there's no chromatography graph, it's not a real COA
• Exact 100% purity: Suspicious — real testing always shows slight variation
• No batch number: Can't trace back to specific production
• No endotoxin testing: For injectables, this is essential
• Template looks like it was made in Word: Professional labs have standardized formats

I have seen fake COAs that are literally photoshopped. Always verify independently if possible.

lisa_labSD said:

COA red flags for certificates of analysis — here's what to look for when reviewing a Certificate of Analysis: No HPLC data: If there's no…

This matches mine closely enough to be worth saying so out loud. Posting only so the count is not one.

lisa_labSD said:

COA red flags for certificates of analysis — here's what to look for when reviewing a Certificate of Analysis: No HPLC data: If there's no…

My vendor review relevant to certificates of analysis: ordered 5 times from my current compounder. Consistency has been excellent.

Shipping: Same-day local pickup
Packaging: Professional, discreet, proper labeling with lot/batch numbers
Purity: 98.6% average across orders (Janoshik verified)
Customer service: Responsive within 6 hours
Price: $142/month for tirzepatide 10mg equivalent

lisa_labSD said:

COA red flags for certificates of analysis — here's what to look for when reviewing a Certificate of Analysis: No HPLC data: If there's no…

HPLC results interpretation for certificates of analysis: when you get your Janoshik report back, here's what the numbers mean:

• Purity %: Should be >97%. Below 95% is concerning.
• Retention time: Should match reference standard for the peptide
• Related substances: Degradation products should be <2% total
• Single impurity: No individual impurity should exceed 1%

My last batch: 99.2% purity, 0.0% total related substances. Clean chromatogram with single sharp peak at expected retention time. Exactly what you want to see.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.