Tirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide

A narrower follow-up, since the general answer is now clear:

Was that from a primary source or from a summary of one?

DoseLogDan said:

The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

DoseLogDan said:

The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

Correct me if the detail matters more than I have assumed.

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.

From the other side of the consultation, briefly. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.