Tirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide

labquiet_amy said:

If you are going to change something, change one thing and give it long enough to express itself.

I read this differently from labquiet_amy, on substance rather than tone. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

labquiet_amy said:

If you are going to change something, change one thing and give it long enough to express itself.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

labquiet_amy said:

If you are going to change something, change one thing and give it long enough to express itself.

Thank you — that is the clearest version of this I have read, and I have read a lot of them.

From the other side of the consultation, briefly. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Dr.PathRoch said:

There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Adding a me-too, because a thread of one person's experience is not much use. Posting only so the count is not one.