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ForumsDosing & ProtocolsTirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide Page 10

Tirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide

Dr.Martinez Mon, Feb 19, 2024 at 5:20 PM 181 replies 34,127 viewsPage 10 of 20
MaxMetOK
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Apr 22, 2024 at 10:27 AM#46

Following on from julia.endo — and this may be the naive question:

Why the interval is four weeks rather than two, and whether a slower ladder gets to the same place?

41 16PharmHunterJen, TomTeleRx, DoseLogDan and 38 others
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Dr.Martinez
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Apr 24, 2024 at 1:38 PM#47

Closing the loop on my own question.

Reporting back after another eight months at the same dose. Still losing slowly, no new side effects, and no reason I can find to climb further.

Last edited: Apr 24, 2024 at 6:38 PM
40 15traveltech_sara, AttorneyGrant, DebRD_ATL and 37 others
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pam_columbus
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Apr 26, 2024 at 4:47 PM#48
anders_CPH said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

Last edited: Apr 26, 2024 at 10:47 PM
39 14Dr.LipidDallas, alex_tucson, kevin_tulsa and 36 others
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Dr.RaviCardio
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Apr 28, 2024 at 7:55 PM#49
anders_CPH said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

That reframing is the part I needed.

38 13hans_munich, jason_sac26, chris_chi24 and 35 others
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Dr.SurgeonPGH
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Apr 30, 2024 at 11:02 PM#50

Clinical perspective, offered as context rather than as advice. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Worth separating that from the titration schedule, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

16 16B12Beth, RickReta_CO, PharmHunterJen and 13 others
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