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ForumsNutrition & SupplementationProbiotics on GLP-1 — anyone have experience? Page 2

Probiotics on GLP-1 — anyone have experience?

PeptideSynthNJ Wed, Jan 8, 2025 at 10:29 PM 12 replies 1,744 viewsPage 2 of 3
BethLabQueen
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Jan 10, 2025 at 3:40 AM#6
PeptideSynthNJ said:
On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie.

DEXA scan update relevant to protein intake:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass252 lbs222 lbs199 lbs
Fat mass102 lbs72 lbs49 lbs
Lean mass155 lbs151 lbs156 lbs
Body fat %45%31%23%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The protein intake discussion needs to include body comp data, not just scale weight.

9 4maya_sedona, stefan_berlin, Dr.EM_Chicago and 6 others
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jennifer_SEA
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Jan 10, 2025 at 3:18 PM#7

A narrower follow-up, since the general answer is now clear:

Whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be?

Last edited: Jan 10, 2025 at 9:18 PM
8 3Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 5 others
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Dr.PathRoch
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Jan 11, 2025 at 2:56 AM#8
BethLabQueen said:
DEXA scan update relevant to protein intake: Scanned at months 0, 6, and 12.

Adding the part of the answer the thread has not reached. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Last edited: Jan 11, 2025 at 8:56 AM
7 2WendyG_ATL, SaraMom3, Dr.MetabolicMD and 4 others
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PeptideSynthNJ
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Jan 11, 2025 at 2:34 PM#9

Closing the loop on my own question.

Reporting back — setting the target on reference weight rather than current weight turned an impossible number into a boring one.

Last edited: Jan 11, 2025 at 6:34 PM
6 1MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 3 others
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lori_vegas
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Jan 13, 2025 at 10:21 PM#10
Dr.PathRoch said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Agreed on the target, with the caveat that reference weight and current weight are different numbers. Using current weight at the start of a large loss produces a target that is both unachievable and unnecessary.

Happy to go further on any of that.

Last edited: Jan 14, 2025 at 12:21 AM
8 8Dr.PathRoch, mona_PHX, andrew_nyc and 5 others
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