Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
LipidDoc_ATL said:If two explanations both fit, the useful question is which one predicts something the other does not.
Can confirm. Same sequence, different timescale.
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Browse GL BiochemLipidDoc_ATL said:If two explanations both fit, the useful question is which one predicts something the other does not.
There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.