Digestive enzyme supplementation — does it help with GLP-1 GI symptoms?

Dr.ObesityMed said:

The RDA is the wrong reference and it is worth understanding why.

I will push back on the powder-first advice. It works and it also trains people out of eating food, and when the drug stops the habits are what remain. Getting protein from meals is slower and holds up better afterwards.

Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

JessicaH_TX said:

I will push back on the powder-first advice.

Adding the part of the answer the thread has not reached. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

A narrower follow-up, since the general answer is now clear:

Whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be?

Reporting back.

Reporting back — setting the target on reference weight rather than current weight turned an impossible number into a boring one.